Senior Research Associate/Associate Scientist, Biomolecular Interaction Department: Lab Science Employment Type: Full Time Location: San Mateo, CA Description The Role: BigHat Biosciences is seeking a self-motivated individual for a Senior Research Associate or Associate Scientist role* in the Protein Sciences team to develop label-free assays for characterizing antigen-antibody interactions. Your position will interface regularly with the Discovery Medicine, Production, and Automation teams to support all aspects of biophysical characterization of antigen-antibody binding in a fast-paced and multidisciplinary environment. * At BigHat we believe in titles that commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate. Key Responsibilities * Design, develop, and perform kinetic experiments to study antigen-antibody interactions using label-free techniques * Troubleshooting of kinetic experiments on both BLI and SPR platforms * Perform epitope binning and quantitation experiments * Develop and onboard kinetic assays for screening antibodies in a high-throughput manner * Write and transfer standard operating protocols (SOPs) for use on the Milliner Platform * Keep a detailed record of all experiments using BigHat's documentation tools, and clearly communicate results and challenges * Present experimental plans and results during regular meetings with manager and science teams Skills Knowledge and Expertise * B.S. with 5+ or M.S. with 3+ years of work experience in industry * Experience using label-free biophysical techniques to study antigen-antibody interactions * Extensive experience in developing, executing, troubleshooting SPR and BLI experiments for kinetics, quantitation, and epitope binning * Good record keeping skills using LIMS and electronic notebooks * Excited to work with diverse, cross functional teams to onboard new assays and disseminate results * Prior experience with automation is preferred Compensation For SRA: $[100 - 120]K For Associate Scientist: $[120 - 140]K