The Chan Zuckerberg Initiative was founded by Priscilla Chan and Mark Zuckerberg in 2015 to help solve some of society's toughest challenges - from eradicating disease and improving education to addressing the needs of our local communities. Our mission is to build a more inclusive, just, and healthy future for everyone.
The Team
CZI supports the science and technology that will make it possible to help scientists cure, prevent, or manage all diseases by the end of this century. While this may seem like an audacious goal, in the last 100 years, biomedical science has made tremendous strides in understanding biological systems, advancing human health, and treating disease.
Achieving our mission will only be possible if scientists are able to better understand human biology. To that end, we have identified four grand challenges that will unlock the mysteries of the cell and how cells interact within systems - paving the way for new discoveries that will change medicine in the decades that follow:
* Building an AI-based virtual cell model to predict and understand cellular behavior
* Developing state-of-the-art imaging systems to observe living cells in action
* Instrumenting tissues to better understand inflammation, a key driver of many diseases
* Engineering and harnessing the immune system for early detection, prevention, and treatment of disease
CZI's work in science includes grantmaking programs, open-source software development, and close collaboration with the Chan Zuckerberg Biohub Network. The CZ Biohub Network includes the San Francisco, Chicago, and New York Biohubs as well as the Chan Zuckerberg Imaging Institute. CZI also collaborates with institutional partners like the Kempner Institute for the Study of Natural & Artificial Intelligence at Harvard University. Join us in accelerating science.
The Opportunity
As a manager of software engineering in the Science Technology Organization, you would be leading a group of highly motivated and talented engineers to build cloud applications on latest technologies that scientists rely on every day in ways that enable them to draw more meaningful conclusions, or biological insights, more quickly. By making our tools, methods, and quality data sets accessible to a diverse set of scientists, clinicians, and patient communities, we contribute to the rate at which biomedical science can advance human health.
The Data Services team manages and processes scientific datasets specifically designed to enable biological modeling. It is responsible for data validation, wrangling, testing, storage, and retrieval. We handle over 89 million unique cells worth of single cell transcriptomic data, over 15 thousand cryoET tomograms that are in imaging datasets as large as 20TB and counting, and will be expanding to support larger scale and additional imaging, sequencing, and literature modalities. Our resources provide access to open source data that is structured and used by tens of thousands of scientists each month to quickly query and form hypotheses on understanding how genetic variants in cells impact disease risk, define drug toxicities, and eventually discover better therapies.
As an Engineering Manager on the Data Services - Pipelines team, you will help manage all the data pipeline needs for our platforms, CELLxGENE Discover, CryoET, as well as the new platform we are building that has a focus on data for AI and the virtual cell. This would include data ingestion, validation, and transformation needs in order to enable scientists to further interrogate our very large and growing corpus of data. You will enable the ingestion of billions of cells worth of data for the purpose of AI modeling, leading the team to think more cohesively and strategically on how we might enable the ingestion and curation of scientific data at scale. This role will lead a software engineering team, working with Product Managers, UX Designers and Researchers, Data Scientists, Application Scientists, Computational Biologists and possibly other roles and partners to design, build and maintain data pipelines for our scientific data.
Responsibilities would include creating and maintaining data pipelines that support multiple CZI products over time. Products have included:
* CryoET Data Portal - The portal provides biologists and developers open access to high-quality, standardized, annotated data they can readily use to retrain or develop new annotation models and algorithms
* CZ CELLxGENE - A rich data platform with interfaces that enable any computational or biological expert to understand the molecular function of cells and tissues
* Virtual Cell Platform - A platform for scientists to build, collaborate and contribute to the AI powered virtual cells which would enable scientists to explore the molecular underpinnings of human health and diseases
No prior biology experience is required for this role. You will have the opportunity to pair with Computational Biologists to develop solutions for our users and be able to learn about biology from experts on our team.
What You'll Do
* Lead a backend engineering team who develops and supports data pipelines, migrations, and schema .
* Work cross-functionally with internal and external partners to develop and deliver on the roadmap and plan the long-term strategy for the team.
* Participate in and encourage appropriate software development practices to deliver frequent value to our users and enable continuous feedback loops.
* Guide the team on technical decisions and oversee that best practices are being followed. Ensure quality in the work we deliver. Be a hands-on manager to the team.
* Provide mentoring and career development support to direct reports.
* Hire and onboard engineers to fill resource gaps while building out a diverse team.
What You'll Bring
* 5+ years of experience in Software Engineering, with 3+ years of engineering leadership experience (as a people manager).
* Worked with an interdisciplinary team to shape product requirements and designs, and deliver software solutions.
* Experience building data pipelines deployed in production environments.
* Ability to coach and develop engineers' skills and careers while creating an inclusive environment.
* Ability to contribute to software design discussions and decisions.
Compensation
The Redwood City, CA base pay range for this role is $214,000 - $321,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.
Benefits for the Whole You
We're thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.
* CZI provides a generous employer match on employee 401(k) contributions to support planning for the future.
* Annual benefit for employees that can be used most meaningfully for them and their families, such as housing, student loan repayment, childcare, commuter costs, or other life needs.
* CZI Life of Service Gifts are awarded to employees to "live the mission" and support the causes closest to them.
* Paid time off to volunteer at an organization of your choice.
* Funding for select family-forming benefits.
* Relocation support for employees who need assistance moving to the Bay Area
* And more!
If you're interested in a role but your previous experience doesn't perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.
Application deadline for this role is Monday, May 19th.
Explore our work modes, benefits, and interview process at www.chanzuckerberg.com/careers.
#LI-Hybrid