Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. This is a laboratory research position for a graduate student currently enrolled in a graduate degree program in physics, engineering or a related field and is working in a research lab. This research is conducted independently under the supervision of the principal investigator on a project focused on the development of a synthetic aperture multiphoton microscope for 3D tissue imaging with digital adaptive optics (DAO). Research projects will prepare the incumbent to work fully independently on a department level and original research in the future. The research conducted and work performed is in fulfillment of their degree program requirements. Essential Functions: * Assemble the laser scanning multiphoton microscope. * Optimize code for 3D digital reconstruction * In collaboration with the PI, implements digital adaptive optics to optimize the microscope for intravital imaging of deep tissue * Perform intravital imaging of mouse skull bone marrow * Benchmark the microscope performance * Develop methods for image analysis and quantification * Organize and document all research data * In collaboration with the PIs, drafts manuscripts and serves as a co-author on publications in journals and presentations at professional conferences and scientific meetings * Wears personal protective equipment as required Job Summary Summary Is a currently enrolled student in a graduate degree program in medicine, biological sciences or related, and is working in a research lab. This research is conducted independently under the supervision of the principal investigator on projects focused on transplantation immunology. Research projects will prepare the incumbent to work fully independently on department level and original research in the future. The research conducted and work performed is at least partially in fulfillment of their degree program requirements. Does this position require Patient Care? No Essential Functions * Designs experiments and modifies techniques as necessary to meet research and/or experimental needs. * Collects and records study data, as well as maintains laboratory notebooks. * Designs, as well as executes research projects, and participates in large animal experiments and laboratory research. * Synthesizes and interprets information obtained from the experiments, performs data analysis using advanced statistical techniques. * In collaboration with the PIs, drafts manuscripts and serves as a co-author on publications in journals and presentations at professional conferences and scientific meetings. * Interprets results, develops new investigative techniques and in collaboration with the PI, determines the most appropriate direction of research. * Participates and presents in Lab meetings and research seminars. * Provides functional guidance to technical and animal care personnel involved in projects. * Works safely within the laboratory environment and in performing work duties. * Wears personal protective equipment as required. Qualifications Education Bachelor's Degree Related Field of Study required Can this role accept experience in lieu of a degree? No Licenses and Credentials Experience Current enrollment in a graduate degree program 0-1 year required Knowledge, Skills and Abilities * Must be capable of performing and interpreting assay data related to the specific research lab. * Must be self-motivated and able to work independently. * Ability to work carefully, accurately and consistently with instruction or protocol. * Must be able to work safely and properly use protective equipment. * Proficiency in Word, PowerPoint, Excel, and Internet searches. * Excellent verbal and written communication skills. Additional Job Details (if applicable) Remote Type Onsite Work Location 185 Cambridge Street Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) EEO Statement: The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.